In the TUNEL assay, TdT enzyme catalyzes the addition of labeled dUTP to the 3′- ends of the internucleosomal DNA strand breaks that are a hallmark of apoptosis. The CF™488 TUNEL Assay Apoptosis Detection Kit employs dUTP conjugated to the exceptionally bright and photostable CF™488 green fluorescent dye, for single step fluorescent TUNEL labeling of fixed cells or tissues for analysis by fluorescence microscopy or flow cytometry.
Compatible with the NucleoCounter® NC-3000™
Parrish and Xue (2006). Chromosoma 115: 89-97; Gold et al. (1994). Lab Invest. 71(2):219-25.
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