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Dihydrorhodamine 123

89.42

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Catalog #: 10055.

Product Description

Dihydrorhodamine 123 is the reduced form of rhodamine 123 (70010), which is a commonly used fluorescent mitochondrial dye. Dihydrorhodamine 123 itself is non-fluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 123 that accumulates in mitochondrial membranes (1). Dihydrorhodamine 123 is useful for detecting reactive oxygen species including superoxide (in the presence of peroxidase or cytochrome c) (2,3) and peroxynitrite (4,5). Also see dihydrorhodamine 123 dihydrochloride (10056), a more stable and water soluble form of dihydrorhodamine 123.

  • White solid soluble in DMSO
  • Store at -20°C and protect from air and light, especially when in solution
  • C20H18N2O3
  • MW: 346
  • [109244-58-8]

1. Br J of Pharmacol (2010) doi: 10.1111/j.1476-5381.2010.01120.x
2. J Immunol Meth 178, 89 (1995).
3. Biochemistry 34, 3544 (1995).
4. Eur J Biochem. 217, 973 (1993).
5. Arc Biochem Biophys 302, 348 (1993).

MSDS (PDF): MSDS 10055

10 mg

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

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Please note that products with recommended storage at 4°C or -20°C may ship at ambient temperature. This will not affect product performance. When you receive the product, place it under the recommended storage conditions.

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