The amine reactive succinimidyl ester of MB (methylene blue) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugates has a blue color that are able to complex with nucleic acids. Methylene blue is a well known redox dye which can be reversibly reduced to its colorless leuco form. Upon oxidation, the blue color of the dye is recovered.
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