NAO is a mitochondrial dye whose staining is not dependent on mitochondrial membrane potential,unlike JC-1 (70011) and Rhodamine 123 (70010). NAO has been used to study multidrug resistanceand to measure changes in mitochondrial mass during apoptosis (3).
- λEx/λEm (MeOH) = 495/522nm
- ε (MeOH) = 63,000
- Orange solid soluble in DMSO or DMF
- Store at 4°C and protect from light, especially in solution
- MW: 473
Compatible with the NucleoCounter® NC-3000™
1. Cytometry 9, 206 (1988).
2. Cancer Res 51, 4665 (1991).
3. Exp Cell Res 214, 323 (1994).
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