Staurosporine is a potent and cell-permeable inhibitor of a wide variety of protein kinases (1,2) including protein kinase C (IC50 = 0.7 nM), protein kinase A (IC50 = 7 nM), and protein kinase G (IC50 = 8.5 nM). Staurosporine induces apoptosis in human neuroblastoma cells and chick embryonic neurons (3,4).
- Soluble in DMSO or ethanol
- Store at -20°C
- MW: 466.20
1. Biochem Biophys Res Commun. 158, 105 (1989).
2. Biochem Biophys Res Commun. 135,
3. Neuropharmacology 36, 811 (1997).
4. J. Neurochem. 66, 1418 (1996).
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