A-23187 Free Acid



Product Description

A-23187, also known as Calcimycin or Calcium Ionophore III, is a calcium ionophore that rapidly equilibrates intracellular and extracellular calcium concentrations. It is commonly used for in situ calibrations of fluorescent calcium indicators. The ionophore allows Mn2 to enter the cells and quench intracellular fluorescence of calcium indicators.

  • White solid soluble in DMSO
  • Store at 4°C and protect from light
  • C29H37N3O6
  • MW: 523.6
  • [52665-69-7]

Also see 4-bromo A-23187 (59006). Because 4-bromo A-23187 is nonfluorescent, it is preferred over the blue fluorescent A-23187 for calibrations of UV-excited Ca2+ indicators such as Indo-1 and Fura-2 in order to keep background fluorescence to a minimum.

1. Anal Chem 61, 382 (1989).

2. FASEB J 8, 639 (1994).
3. Merck Index 12, 1678.
4. Science 217 (4563), 943 (1982).

MSDS (PDF): MSDS 59001

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

Expedited shipment may be requested at time of checkout.

Please note that products will be shipped at ambient temperature. This will not affect performance if the products are kept at the indicated temperature for long term storage. Please refer to the package insert for correct storage conditions.

More information about product handling and shelf life