CF680R Transferrin (human)



Product Description

Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron-binding domains that binds up to two Fe(III) atoms for delivery to vertebrate cells through receptor-mediated endocytosis. After binding to its receptor on the cell surface, transferrin is rapidly internalized by invagination of clathrin-coated pits with formation of endocytic vesicles, the acidic environment favors dissociation of iron from the transferrin-receptor complex. Following the release of iron, the apotransferrin is recycled to the plasma membrane where it is released from its receptor to scavenge more iron. Human transferrin is labeled with our bright and photostable CF™ dyes for investigation of endocytosis by microscopy. Download the product protocol to view the full list of conjugates and their excitation/emission wavelengths.


Flyer (PDF): FL-CF680R

MSDS (PDF): MSDS 00086

Protocol (PDF): PI-CFTransferrin

1 mg

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

Expedited shipment may be requested at time of checkout.

Please note that products will be shipped at ambient temperature. This will not affect performance if the products are kept at the indicated temperature for long term storage. Please refer to the package insert for correct storage conditions.

More information about product handling and shelf life