Product Description

D2R (Rhodamine 110, bis-(L-aspartic acid amide), ditrifluoroacetic acid salt) is a general substrate for caspases including caspases 3 and 7. Unlike other fluorogenic substrates for caspases, D2R appears to be membrane-permeant, and thus can be used to measure caspase activity in live cells without osmotic shock for flow cytometry studies, as well as for cell extracts. For real-time detection of caspase-3 activity in intact cells, see our novel NucView™488 Caspase-3 Substrate.

  • λExEm of end product (R110) = 496/520 nm
  • Off-white to pink solid soluble in DMSO
  • Store at -20°C and protect from light
  • C32H26F6N4O13
  • MW: 788.57

1. Biochemistry 38, 13906 (1999).

MSDS (PDF): MSDS 10210

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

Expedited shipment may be requested at time of checkout.

Please note that products will be shipped at ambient temperature. This will not affect performance if the products are kept at the indicated temperature for long term storage. Please refer to the package insert for correct storage conditions.

More information about product handling and shelf life