Fluo-3, AM ester



Product Description

Membrane-permeant AM ester form of Fluo-3 that can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluronic F-127, a mild detergent, is often used as a dispersing agent to facilitate dye loading. Fluo-3 AM ester itself does not bind Ca2+, but it is readily hydrolyzed to fluo-3 by endogenous esterases once the dye is inside the cells. An important application of Fluo-3 AM ester is its use in high throughput drug screening.

  • Orange red solid soluble in DMSO
  • Store -20°C and protect from light, especially when in solution
  • C51H50Cl2N2O23
  • MW: 1129.9
  • [121714-22-5]

For information on fluo-3, see #50010.

1. Cell Calcium 11, 121 (1990).
2. J Cell Biol 111, 183 (1990).
3. J Biol Chem 268, 2134 (1993).

MSDS (PDF):MSDS 50013, MSDS 50014, MSDS 50016

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