Product Description

L-NIL (N6-(1-Iminoethyl)-lysine, hydrochloride) is a potent and selective inhibitor of nitric oxide synthase that exhibits about 28-fold greater selectivity for inducible nitric oxide synthase (IC50 = 3.3 uM) than for the rat brain constitutive enzyme (IC50 = 92 uM). It exhibits about 10-fold greater inhibitory potency than NG-monomethyl-L-arginine in inhibiting γ-interferon-induced NO2– production (IC50 = 460 nM). Also see our NOS inhibitor kit (249).

  • White solid soluble in water
  • Store at -20°C
  • C8H18ClN3O2
  • MW: 223.7
  • [150403-89-7]

1. J Med Chem 77, 3886 (1994).
2. Eur J Pharmacol 294(2-3), 703 (1995).
3. Biochem Pharmacol 51(4), 383 (1996).

MSDS (PDF): MSDS 00242

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

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Please note that products will be shipped at ambient temperature. This will not affect performance if the products are kept at the indicated temperature for long term storage. Please refer to the package insert for correct storage conditions.

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